In a living being, proteins make up roughly everything: from the molecular machines running every cell’s metabolism, to the tip of your hair. Encoded in the DNA, a protein may be represented as a ...

A team of researchers has revealed the structure of a protein complex which is an important regulator of cellular degradation processes. Proteins are indispensable components in living organisms. They ...

Of the three groups of rotavirus that cause gastroenteritis in people, called groups A, B and C, groups A and C affect mostly children and are the best characterized. On the other hand, of group B, ...

Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA.

A year after demonstrating its AlphaFold program could tackle the decades-old problem of predicting the final working shapes of proteins from just their building blocks—and making it open to the ...

In an effort to reveal the inner workings of a protein that serves as a cell's damage detection system, scientists at Johns Hopkins and the Ludwig-Maximilians-University Munich (LMU) have published ...

In the rapidly advancing field of computational biology, a newly peer-reviewed review explores the transformative role of deep learning techniques in revolutionizing protein structure prediction. The ...

This year’s Lasker Basic Medical Research Award recognizes the contributions of Demis Hassabis and John Jumper for their invention of the AlphaFold artificial intelligence (AI) system, which predicts ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the membrane proteins myoferlin and dysferlin using high-resolution cryo-electron ...

TnpB adopts a bilobed structure consisting of the REC lobe and NUC lobe. The REC lobe comprises WED and REC domains, whereas the NUC lobe comprises the RuvC and TNB domains. TnpB assembles with a ωRNA ...